A
message for seniors: as you get
older the biological reserves are less, so too is the bioactivity of
supplements; thus a higher dose is needed to produce a positive result.
Because the body’s reserves are less, the
benefits of exercise, healthful diet, and healthful supplements yield a greater
benefit. Also increasing
the benefit of
healthful choices is the fact that the risk of chronic and acute conditions
such as cancer, heart attack, macular degeneration is much greater:
those interventions which reduce their risks
bear a greater statistical benefit. For
example a person who starts jogging at 60 for 10 years will on an average
benefit more that a person at 30 years at reducing the risk of heart attack and
reducing insulin resistance. The
same increased
benefits apply to the taking supplements, hormones, and aspirin. ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^
The most important thing to prolonging life is to avoid the worst six; average loss for tobacco 7 years, obesity 5 years, high carbohydrate and low saturated fat diet 5
years, polypharmacy (taking more than 4 drugs) 5 years, recreational drugs 4 years, and sedentary lifestyle
4 years. Those who feel better physically at middle age are less like to do
the worst six. These negative results are averages from populations. Thus
a person who eats a poor diet is more likely to be sedentary and take over 4 drugs.
There are two sides to measuring life, one of duration the other of quality. Those things that improve quality also improve longevity. For
a number of reasons, to complex to set out here, hormone replacement contributes to quality of life. For quality of life, vigorous exercise is best; however, this should be augmented with either female hormones or male hormones. In fact it seems that women, since there testosterone
level drop past menopause, that they would benefit with a restoration of this hormone to a youthful level. Vigorous exercise improves both quality and
longevity a Finish study shows. A very marked reduction in coronary death
of 65% for 2009 Finish male athletes who competed in international competition between 1920 and 1965 in either running or
cross country skiing, and died between 1971 and 1995. Moreover, this group,
compared to the general populace experience only 108 deaths versus an expected 189, a reduction of 57%. A study of senior who ran or did other vigorous exercise, found that death and disability were
delayed by over 8 years. Aging has many causes, most prominent are: (1) the reduction in performance
of the mitochondria due to reactive chemicals produced therein; (2) the braking of hydrogen bonds especially the cystine to
an adjacent hydrogen, which causes a modification of the shape of polypeptides and proteins; (3) oxidation and glycation of
proteins, and (4) senescence. By making the mitochondria work less (being 25% below thin body weight) a number of animal studies have yielded an increase in the life expectancy of about 25%, thought not in maximal life
expectancy. Vigorous exercise, an
aspirin a day, avoiding the deadly three, and hormone replacement are the best ways to extend
life and improve its quality.
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