A typical baby born in this country in 1900
                           was expected to live to about age 45. Today, life expectancy at birth is about 78 and climbing. Americans are living longer
                           and healthier lives than ever before. But we have never been more concerned about the risks and costs associated with new
                           prescription drugs and medical devices.
                           Rising health-care costs and safety problems
                           with FDA-approved products such as the painkiller Vioxx, drug-coated stents and implanted defibrillators have led some to worry
                           that recent medical innovations may be doing us more harm than good. 
                           The debate over the relative speed (and caution)
                           with which new medical products should be approved has crystallized in Congress as it crafts legislation reauthorizing the
                           Prescription Drug User Fee Act. Since 1992 the act has been a critical funding source for the Food and Drug Administration. Lawmakers should be careful to balance safety and cost concerns, and additional
                           regulatory burdens for product developers, with benefits to patients -- specifically, the measurable impact that new medical
                           innovations have on Americans' longevity and quality of life.
                           How have medical innovations affected American
                           health? In a study the Manhattan Institute is releasing today -- "Why Has Life Expectancy Increased More in Some States
                           Than in Others?" -- I explain that incremental medical innovations, particularly the use of newer drugs, have played a major
                           role in increasing American longevity in recent years.
                           I began by looking at the interstate variation
                           in life expectancy. Most Americans would probably be surprised to discover that, on average, residents of Hawaii (81.3 years) and Minnesota (80.3 years) lived six or seven years longer than residents of Mississippi and Louisiana (74.2 years).
                           And while U.S. life expectancy increased by
                           2.33 years from 1991 to 2004, some jurisdictions -- the District of Columbia (5.7 years), New York (4.3 years), California (3.4 years) and New Jersey (3.3 years) -- led the way, while others, such as Oklahoma (0.3 years), Tennessee (0.8 years) and Utah (0.9 years), trailed the national average by significant margins. (Between
                           1991 and 2004, life expectancy in Maryland and Virginia increased by 2.5 and 2.6 years, respectively.)
                           To find out why this longevity "increase gap"
                           exists, I examined several factors that researchers generally agree affect life expectancy, including medical innovation,
                           obesity rates, smoking and HIV-AIDS infection rates. While each of these factors had an impact on longevity, the most important
                           factor was medical innovation. In particular, I found that longevity increased the most in those states where access to newer
                           drugs -- measured by their mean "vintage," or FDA approval year -- in Medicaid and Medicare programs has increased the most.
                           According to my econometric model, about two-thirds
                           (63 percent) of the potential increase in longevity during this period -- the increase that would have occurred if obesity,
                           income and other factors had not changed -- can be attributed to the use of newer drugs. In fact, for every year increase
                           in average drug vintage there was an almost two-month gain in life expectancy.
                           Increasing access to newer drugs was not associated
                           with above-average annual spending on health care; and the use of newer medicines seems to have increased labor productivity
                           (output per employee) by about 1 percent per year, perhaps because of reduced absenteeism from chronic ailments. Overall,
                           my findings contradicted the common assumption that advances in medical technology automatically result in increased health-care
                           expenditures.
                           Congressional debate over the Prescription
                           Drug User Fee Act is a microcosm of the national debate over the appropriate balance between safety and rapid access to new
                           and sometimes very expensive medical innovations. While this debate is complex, my research indicates that the best way to
                           achieve sustained improvements in health, longevity and productivity is by continuing to support policies that encourage medical
                           innovation and the new medical goods and services it produces.
                           By Frank R. Lichtenberg is
                           a professor at Columbia University School of Business, and he has been in the pay of big PhARMA.